A Data-Powered Deep Dive into the Future of RNA Therapeutics
RNA therapeutics continues to impress. In the first half of 2025, Beacon RNA tracked 5,554 active drugs and 2,544 trials, capturing a field that is expanding, maturing, and diversifying all at once. The 13% surge in pipeline assets since January reflects an industry turning bold ideas into clinical impact.
Our mid-year review delivers unparalleled visibility into the state of RNA R&D, covering new drug modalities, shifting disease priorities, evolving delivery systems, trial dynamics, and investment patterns that are reshaping the therapeutic frontier.
Report Contents
The Drug Landscape
Explore a pipeline that grew by 650+ RNA therapies in just six months, with circular RNA gaining momentum and siRNA holding strong.
The Trial Landscape
Track over 2,500 active trials and shifting priorities in early-phase research, where oncology and rare diseases dominate 2025 activity.
The Commercial Landscape
Uncover $50B+ in RNA-related deals, as investors lean into late-stage programs and biotech partnerships become more selective.
The Future of RNA Therapeutics
Examine how next-gen delivery platforms are expanding RNA’s reach beyond the liver, unlocking potential in neurology and oncology.
Regulatory Announcements
Review the regulatory pulse of 2025, with mRNA and siRNA therapies leading announcements and securing continued momentum.
Previous RNA Landscape Reviews
RNA 2024 H1 Landscape Review
An analysis of the RNA landscape in H1 of 2024
RNA 2024 Landscape Review
Uncover the key 2024 RNA breakthroughs and stay ahead in the rapidly evolving RNA landscape.
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Learn More About RNA
- The Most Comprehensive Way to Search the RNA Drug Development Landscape: Unique search ontologies based on RNA drug and trial characteristics
- Market Leading Approach to RNA Preclinical & Clinical Data Curation: Manual curation of key RNA research and development data points by RNA research scientists
- Seamlessly Integrate Commercial & Scientific Data all in One Place: Search RNA company and deal data based on their pipeline and technologies.
- Unrivalled Granularity in Reports & Analysis: Our search ontology and technology indexing enable comprehensive analysis not seen elsewhere.
What is Beacon?
Beacon is a world leading data analysis tool for preclinical and clinical trial information. With unrivalled granularity of search function, data quality, and exhaustiveness, Beacon provides timely information and gives you confidence to progress your targeted drug therapies to patients.
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