Emerging Themes Shaping Gene Therapy Development in 2025
Gene therapy science has never been so strong, and the accelerating innovation surrounding this market has seen three first-time approvals in 2025 so far – compared to just one in 2024. With diversifying modalities such as DNA therapies surging by over 20%, paired with the expansion of complex indications giving way to landmark progress in Parkinson’s and lysosomal storage diseases, and a 9% increase in non-viral technologies, it is no wonder that we have seen over $10B in financial commitments already this year.
Report Contents
The Drug Landscape
Explore the full drug landscape analysis, spotlight high-potential assets, and uncover where the next big breakthroughs may come from.
The Trial Landscape
Deep dive into the trial landscape, understand trial trends, sponsors, where trials are taking place, and reasons for trial terminations.
The Commercial Market
A review of gene therapy deals, mergers and acquisitions from H1 2025, as well as gene therapy company type and location.
The Future of Gene Therapy
A glimpse into the future trajectory of the gene therapy space, with a focus on potential approvals and upcoming milestones.
Regulatory Announcements
A review of 2025 regulatory announcements so far, including a spotlight on drugs with the most regulatory activity and regulatory type.
Previous Gene Therapy Landscape Reviews
Gene Therapy 2024 H1 Landscape Review
An analysis of the Gene Therapy landscape in H1 of 2024
Gene Therapy 2024 Landscape Review
An analysis of the Gene Therapy landscape in 2024
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Learn More About Gene Therapy
- The Most Comprehensive Way to Search the Gene Therapy Development Landscape: Unique search ontologies based on Gene Therapy drug and trial characteristics
- Market Leading Approach to Gene Therapy Preclinical & Clinical Data Curation: Manual curation of key Gene Therapy research and development data points by Gene Therapy research scientists
- Seamlessly Integrate Commercial & Scientific Data all in One Place: Search Gene Therapy company and deal data based on their pipeline and technologies.
- Unrivalled Granularity in Reports & Analysis: Our search ontology and technology indexing enable comprehensive analysis not seen elsewhere.
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